Description

(4As)-1,4A,5,6,11,11B-Hexahydro-11Bβ-Methyl-n-Isopropyl-2H-Benzo[A]Carbazol-5α-Amine is a complex, high-purity organic intermediate belonging to the carbazole alkaloid class, characterized by its specific stereochemistry. This compound matters for its role as a critical building block in advanced pharmaceutical synthesis and fine chemical research, where precise molecular architecture is paramount. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-cancer drug discovery programs.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its complex polycyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex natural product analogs and heterocyclic compounds.
• Material Science Research: Investigated as a potential monomer or dopant for creating specialized organic semiconductors or photoconductive materials due to the carbazole core.
• Catalyst Ligand Development: Its amine functionality and rigid structure make it a candidate for developing novel chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	(4As)-1,4A,5,6,11,11B-Hexahydro-11Bβ-Methyl-n-Isopropyl-2H-Benzo[A]Carbazol-5α-Amine
CAS No.	80787-63-9
Molecular Formula	C19H26N2
Molecular Weight	282.43 g/mol
Synonyms	11bβ-Methyl-1,4a,5,6,11,11b-hexahydro-2H-benzo[a]carbazol-5α-amine, N-Isopropyl; 5α-Amino-11bβ-methyl-1,4a,5,6,11,11b-hexahydro-2H-benzo[a]carbazole; Benzo[a]carbazol-5α-amine derivative; Carbazole alkaloid intermediate; CAS 80787-63-9
EINECS	Contact for details

Quality Control

Our (4As)-1,4A,5,6,11,11B-Hexahydro-11Bβ-Methyl-n-Isopropyl-2H-Benzo[A]Carbazol-5α-Amine is manufactured under strict GMP-like conditions to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.