Description

1-Iodo-2-(Methoxymethoxy)Benzene is a versatile aromatic building block featuring both an iodine substituent and a methoxymethoxy protecting group. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for use in cross-coupling reactions and as a precursor for further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via metal-catalyzed cross-coupling reactions such as Suzuki, Stille, or Sonogashira couplings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the aryl iodide.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for biochemical and diagnostic research applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	1-Iodo-2-(Methoxymethoxy)Benzene
CAS No.	80778-47-8
Molecular Formula	C9H11IO2
Molecular Weight	278.09 g/mol
Synonyms	2-Iodo-1-(methoxymethoxy)benzene; o-(Methoxymethoxy)iodobenzene; 1-Iodo-2-(MOMoxy)benzene; Benzene, 1-iodo-2-(methoxymethoxy)-; (2-(Methoxymethoxy)phenyl)iodide; MOM-protected 2-iodophenol; 2-(Methoxymethoxy)phenyl iodide
EINECS	Contact for details

Quality Control

Our 1-Iodo-2-(Methoxymethoxy)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.