Description

1-(5-Bromothiophen-2-Yl)-3-Chloropropan-1-One is a high-purity, versatile organic building block featuring both bromothiophene and chloropropanone functional groups. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated thiophene core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers and advanced organic electronic materials.
• Chemical Synthesis: An essential building block for coupling reactions (e.g., Suzuki, Stille) and further functionalization due to its reactive bromine and chlorine sites.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	1-(5-Bromothiophen-2-Yl)-3-Chloropropan-1-One
CAS No.	80775-42-4
Molecular Formula	C7H6BrClOS
Molecular Weight	253.54 g/mol
Synonyms	3-Chloro-1-(5-bromothiophen-2-yl)propan-1-one; 1-(5-Bromo-2-thienyl)-3-chloro-1-propanone; 5-Bromo-2-(3-chloropropanoyl)thiophene; 3-Chloro-1-(5-bromo-2-thienyl)-1-propanone; 2-Propanone, 3-chloro-1-(5-bromo-2-thienyl)-; 5-Bromothiophene-2-yl 3-chloropropyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromothiophen-2-Yl)-3-Chloropropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.