Description

Phosphinic Acid, p-(1-Amino-3-Methylbutyl)- is a specialized organophosphorus compound featuring a unique aminoalkyl substituent. This structural motif makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists and process engineers for creating novel active ingredients and fine chemicals. The compound, identified by CAS No. 80744-65-6, offers a versatile building block for introducing phosphinic acid functionality into target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators with enhanced activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized phosphinate ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: The amino acid-like structure allows its incorporation into peptide analogs to modify stability and biological activity.
• Flame Retardant Synergist: Investigated as a component in advanced, nitrogen-phosphorus based flame retardant systems for polymers.
• Chemical Research & Development: A versatile reagent for exploring new reactions and methodologies in organophosphorus chemistry.

Basic Information

Product Name	Phosphinic Acid, p-(1-Amino-3-Methylbutyl)-
CAS No.	80744-65-6
Molecular Formula	C5H14NO2P
Molecular Weight	151.14 g/mol
Synonyms	4-(1-Amino-3-methylbutyl)phosphinic acid; (4-Amino-2-methylbutyl)phosphinic acid; p-(1-Amino-3-methylbutyl)phosphinic acid; 1-Amino-3-methylbutylphosphinic acid; Leucinol phosphinate analog; Phosphinoleucine
EINECS	Contact for details

Quality Control

Every batch of Phosphinic Acid, p-(1-Amino-3-Methylbutyl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including assay (by HPLC/NMR), chiral purity (if applicable), and impurity profile is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.