Description

Methyl 3-(Acetylamino)-5-Nitrothiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct nitro-substituted thiophene core. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel thiophene-based drug molecules, including potential antimicrobials and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro and heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile substrate for further chemical transformations, such as reduction of the nitro group or hydrolysis of the ester.
• Material Science Research: Potential monomer or precursor for creating specialized polymers and organic electronic materials due to the thiophene moiety.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex heterocyclic dyes and colorants.

Basic Information

Product Name	Methyl 3-(Acetylamino)-5-Nitrothiophene-2-Carboxylate
CAS No.	80615-54-9
Molecular Formula	C8H8N2O5S
Molecular Weight	244.22 g/mol
Synonyms	3-Acetamido-5-nitrothiophene-2-carboxylic acid methyl ester; Methyl 3-acetamido-5-nitro-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-(acetylamino)-5-nitro-, methyl ester; 3-Acetylamino-5-nitrothiophene-2-carboxylic acid methyl ester; MANTC
EINECS	Contact for details

Quality Control

Our Methyl 3-(Acetylamino)-5-Nitrothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.