Description

Methyl 3-(Acetylamino)-4-Nitrothiophene-2-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both nitro and acetylamino substituents, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its nitro-thiophene core.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and pigments due to its chromophoric thiophene ring.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 3-(Acetylamino)-4-Nitrothiophene-2-Carboxylate
CAS No.	80615-53-8
Molecular Formula	C8H8N2O5S
Molecular Weight	244.22 g/mol
Synonyms	Methyl 3-acetamido-4-nitrothiophene-2-carboxylate; 3-Acetylamino-4-nitro-thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-(acetylamino)-4-nitro-, methyl ester; Methyl 3-acetylamino-4-nitrothiophene-2-carboxylate; 3-Acetamido-4-nitrothiophene-2-methyl carboxylate; 80615-53-8; MANTC
EINECS	Contact for details

Quality Control

Our Methyl 3-(Acetylamino)-4-Nitrothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.