Description

5-(Hydroxymethyl)-3-Thiophenecarbonitrile is a versatile heterocyclic building block featuring both hydroxymethyl and nitrile functional groups on a thiophene core. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of functional polymers and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of conjugated polymers and organic semiconductors for electronic and optoelectronic devices.
• Chemical Research & Development: A valuable building block in organic synthesis for constructing complex thiophene-containing molecules in academic and industrial R&D labs.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	5-(Hydroxymethyl)-3-Thiophenecarbonitrile
CAS No.	80577-96-4
Molecular Formula	C6H5NOS
Molecular Weight	139.17 g/mol
Synonyms	3-Cyano-5-hydroxymethylthiophene; 5-Hydroxymethylthiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 5-(hydroxymethyl)-; Thiophene-3-carbonitrile, 5-(hydroxymethyl)-; 5-(Hydroxymethyl)thiophene-3-carbonitrile; 3-Cyano-5-(hydroxymethyl)thiophene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and consistency for every batch. Certificates of Analysis (COA) detailing all relevant specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.