Description

2-Mercapto-4-Methoxybenzoic Acid is a specialized organic compound featuring both a carboxylic acid and a thiol functional group on a methoxy-substituted benzene ring. This unique structure makes it a valuable intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working in fine chemical synthesis. The compound is available under CAS NO 80568-44-1.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a benzothiazole or thioether core structure.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions.
• Material Science Research: Investigated for the development of organic electronic materials and polymers due to its electron-donating methoxy group and reactive thiol.
• Chemical Biology Probes: Utilized in the design of probes and inhibitors that target enzymes with cysteine residues in their active sites.

Basic Information

Product Name	2-Mercapto-4-Methoxybenzoic Acid
CAS No.	80568-44-1
Molecular Formula	C8H8O3S
Molecular Weight	184.21 g/mol
Synonyms	4-Methoxy-2-mercaptobenzoic Acid; 2-Sulfanyl-4-methoxybenzoic Acid; 2-Mercapto-p-anisic Acid; 4-Methoxysalicylic Acid Thiol; Benzoic acid, 2-mercapto-4-methoxy-; 2-Thiosalicylic acid 4-methyl ether
EINECS	Contact for details

Quality Control

Our 2-Mercapto-4-Methoxybenzoic Acid is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to confirm identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (by HPLC), related substances, and residual solvents. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.