Description

(R)-1-(4-Bromophenyl)-2,2,2-Trifluoroethanol is a high-value chiral building block and key intermediate in advanced organic synthesis. This compound is critical for the development of pharmaceuticals and agrochemicals due to its trifluoromethyl group and bromophenyl moiety, which impart unique biological activity and metabolic stability. It is primarily sought by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the properties of the trifluoromethyl group.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in medicinal and process chemistry.

Basic Information

Product Name	(R)-1-(4-Bromophenyl)-2,2,2-Trifluoroethanol
CAS No.	80418-12-8
Molecular Formula	C8H6BrF3O
Molecular Weight	255.03 g/mol
Synonyms	(R)-4-Bromo-α-(trifluoromethyl)benzyl alcohol; (R)-1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-ol; (R)-α-(Trifluoromethyl)-4-bromobenzyl alcohol; (R)-p-Bromo-α-(trifluoromethyl)benzyl alcohol; (R)-1-(p-Bromophenyl)-2,2,2-trifluoroethanol; (R)-4-Bromo-α,α,α-trifluorotoluene-α-ol; (R)-BPTFE
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Bromophenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.