Description

3-(1H-Indol-3-Ylsulfanyl)-Propionic Acid is a specialized sulfur-containing indole derivative that serves as a valuable synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for applications such as medicinal chemistry and heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique indole-thioether scaffold.
• Agrochemical Synthesis: Intermediate in the development of new fungicides or plant growth regulators that leverage the biological activity of indole derivatives.
• Bioconjugation & Probe Development: The carboxylic acid and thioether functional groups allow for use in creating biochemical probes or protein conjugation linkers.
• Material Science Precursor: Potential starting material for organic electronic materials or ligands in catalytic systems.

Basic Information

Product Name	3-(1H-Indol-3-Ylsulfanyl)-Propionic Acid
CAS No.	80412-20-0
Molecular Formula	C11H11NO2S
Molecular Weight	221.27 g/mol
Synonyms	3-(3-Indolylthio)propionic Acid; 3-(Indol-3-ylthio)propanoic Acid; 3-(1H-Indol-3-ylsulfanyl)propanoic Acid; 3-(1H-Indol-3-ylthio)propionic Acid; 3-(Indol-3-ylmercapto)propionic Acid; β-(3-Indolylthio)propionic Acid; 80412-20-0; 3-(1H-Indol-3-Ylsulfanyl)-Propanoic Acid
EINECS	Contact for details

Quality Control

Our 3-(1H-Indol-3-Ylsulfanyl)-Propionic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.