Description

Tetramethyl-D12 Orthosilicate is a deuterated isotopologue of tetramethyl orthosilicate, where all hydrogen atoms are replaced by deuterium. This high-purity labeled compound is critical for applications requiring minimal interference from proton signals, such as advanced NMR spectroscopy and mechanistic studies in organic and organometallic chemistry. It serves as a vital reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise isotopic labeling for analytical and synthetic purposes.

Application

• NMR Spectroscopy: Used as an internal standard or solvent in deuterium NMR (²H NMR) and as a silicon-29 (²⁹Si) NMR reference compound due to its isotopic purity.
• Mechanistic Studies: Employed as a labeled precursor in reaction mechanism elucidation, particularly in sol-gel chemistry and silicate formation pathways.
• Isotope Dilution Mass Spectrometry (IDMS): Acts as a high-purity standard for the accurate quantification of silicon-containing compounds in complex matrices.
• Deuterated Material Synthesis: Serves as a key building block for the preparation of other deuterium-labeled silanes, silicones, and hybrid organic-inorganic materials.
• Thin Film & Semiconductor Research: Utilized in chemical vapor deposition (CVD) processes for depositing deuterium-doped silicon oxide films with specific optical and electronic properties.
• Pharmaceutical Research: Applied in metabolic studies and the development of deuterated drugs where isotopic labeling is used to modify pharmacokinetic profiles.

Basic Information

Product Name	Tetramethyl-D12 Orthosilicate
CAS No.	80396-70-9
Molecular Formula	C4D12O4Si
Molecular Weight	176.33 g/mol
Synonyms	Tetramethyl Orthosilicate-d12; Deuterated Tetramethyl Orthosilicate; Tetramethoxysilane-d12; TMOS-d12; Methyl Orthosilicate-d12; Silicon(IV) Methoxide-d12; Tetramethyl-D12 Silicate; Perdeuterated Tetramethyl Orthosilicate
EINECS	Contact for details

Quality Control

Our Tetramethyl-D12 Orthosilicate is produced under stringent conditions to ensure exceptional isotopic and chemical purity, meeting the exacting requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity, and impurity profiles. We adhere to rigorous quality testing protocols to guarantee batch-to-batch consistency and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong alkalis and incompatible materials.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Deuterium Content (NMR)	≥ 99 atom % D
Purity (GC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.