Description

3-Amino-2,5,6-Trimethyl-3H-Thieno[2,3-D]Pyrimidin-4-One is a high-purity, heterocyclic organic compound with the CAS number 80381-63-1, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry. Its fused thienopyrimidinone core structure makes it a valuable scaffold for developing novel therapeutic agents, particularly in oncology and antiviral research. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific enzymes and receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncology Research: Investigated for the development of kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• Antiviral Agent Development: Serves as a precursor in the research and synthesis of compounds with potential antiviral activity.
• Agrochemical Synthesis: Can be utilized in the development of new herbicides or fungicides with novel modes of action.
• Material Science: Potential precursor for organic electronic materials or ligands in catalytic systems.

Basic Information

Product Name	3-Amino-2,5,6-Trimethyl-3H-Thieno[2,3-D]Pyrimidin-4-One
CAS No.	80381-63-1
Molecular Formula	C9H11N3OS
Molecular Weight	209.27 g/mol
Synonyms	3-Amino-2,5,6-trimethylthieno[2,3-d]pyrimidin-4(3H)-one; 2,5,6-Trimethyl-3-amino-3H-thieno[2,3-d]pyrimidin-4-one; 3H-Thieno[2,3-d]pyrimidin-4-one, 3-amino-2,5,6-trimethyl-; 80381-63-1; Thienopyrimidinone derivative; API Intermediate 80381-63-1
EINECS	Contact for details

Quality Control

Our 3-Amino-2,5,6-Trimethyl-3H-Thieno[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.