Description

Ceftiofur is a third-generation cephalosporin antibiotic specifically designed for veterinary use. Its primary value lies in its broad-spectrum efficacy against a wide range of Gram-positive and Gram-negative bacteria, making it a critical tool for managing infectious diseases in livestock. This product is essential for manufacturers in the animal health pharmaceutical industry, formulators of veterinary injectables, and suppliers to large-scale farming operations seeking reliable, high-quality active pharmaceutical ingredients (APIs) for therapeutic and prophylactic applications.

Application

• Veterinary Pharmaceutical Formulations: Primary active ingredient in injectable antibiotic solutions and suspensions for cattle, swine, and poultry.
• Treatment of Bovine Respiratory Disease (BRD): Effective against pathogens like Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni.
• Swine Health Management: Used to treat respiratory infections and control swine bacterial pneumonia.
• Metritis and Mastitis Control: Administered for the treatment of postpartum uterine infections (metritis) in cattle and mastitis in dairy cows.
• Poultry Health: Applied for the control of early mortality associated with E. coli infections in day-old chicks and poults.
• Generic Veterinary Drug Manufacturing: Sourcing of API for the production of cost-effective generic ceftiofur sodium, hydrochloride, or free acid products.
• Feed Additive Premixes: (Where approved) Incorporated into medicated feed for herd-level disease management.

Basic Information

Product Name	Ceftiofur
CAS No.	80370-57-6
Molecular Formula	C19H17N5O7S3
Molecular Weight	523.56 g/mol
Synonyms	Ceftiofur Free Acid; (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; U-64279E; Naxcel® (brand name for sodium salt); Excenel® (brand name); Excede® (brand name for crystalline free acid); Cefiocyl; Veterinary Cephalosporin API
EINECS	Contact for details

Quality Control

Our Ceftiofur is manufactured under strict quality management systems to ensure it meets the high standards required for veterinary pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting compliance with in-house specifications is provided with every shipment. We support customers requiring alignment with pharmacopeial standards such as USP or EP for monograph development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and maintain potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.