Description

Isoquinoline-5-Carbaldehyde is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its aldehyde functionality makes it a critical precursor for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, antimicrobial agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Building block for organic semiconductors, fluorescent dyes, and photoactive materials due to its conjugated aromatic system.
• Academic & R&D: Fundamental reagent in heterocyclic and medicinal chemistry research for constructing fused ring systems and exploring structure-activity relationships (SAR).
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance molecules and other high-value specialty chemicals.

Basic Information

Product Name	Isoquinoline-5-Carbaldehyde
CAS No.	80278-67-7
Molecular Formula	C10H7NO
Molecular Weight	157.17 g/mol
Synonyms	5-Isoquinolinecarboxaldehyde; 5-Formylisoquinoline; Isoquinoline-5-carboxaldehyde; 5-Carbaldehydeisoquinoline; 1-Azanaphthalene-5-carbaldehyde; 5-Aldehydoisoquinoline; NSC 403119; 80278-67-7
EINECS	Contact for details

Quality Control

Our Isoquinoline-5-Carbaldehyde is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades, including pharmaceutical intermediates standard, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.