Description

2H-Benzimidazole-2-Thione,1,3-Dihydro-1-(2-Propynyl)-(9Ci) is a specialized heterocyclic organic compound, identified by CAS number 80276-21-7, that serves as a versatile synthetic intermediate and building block in advanced chemical synthesis. Its unique benzimidazole-thione core functionalized with a propargyl group makes it a valuable precursor for developing novel pharmaceuticals, agrochemicals, and functional materials. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, such as fungicides or herbicides.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and specialty materials.
• Chemical Synthesis: Acts as a versatile precursor for further functionalization via reactions at the thione or alkyne groups.
• Bioconjugation & Probe Development: The propargyl group enables click chemistry reactions for labeling and bioconjugation applications in life sciences.
• Catalyst Ligand Synthesis: Potential use in constructing complex ligand systems for metal catalysis.

Basic Information

Product Name	2H-Benzimidazole-2-Thione,1,3-Dihydro-1-(2-Propynyl)-(9Ci)
CAS No.	80276-21-7
Molecular Formula	C10H8N2S
Molecular Weight	188.25 g/mol
Synonyms	1-Propargyl-2-mercaptobenzimidazole; 1-(2-Propynyl)-1,3-dihydro-2H-benzimidazole-2-thione; 1-(Prop-2-yn-1-yl)-1H-benzo[d]imidazole-2(3H)-thione; 1-Propargylbenzimidazole-2-thiol; 2-Mercapto-1-propargylbenzimidazole; NSC 403119; 1-(Prop-2-ynyl)-1,3-dihydro-2H-benzimidazole-2-thione
EINECS	Contact for details

Quality Control

Our 2H-Benzimidazole-2-Thione,1,3-Dihydro-1-(2-Propynyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.