Description

1-Methyl-9-Hydroxy-1,2,3,9A-Tetrahydro-1-Azafluorene Hydrochloride is a high-purity organic compound, specifically a tetrahydroazafluorene derivative, supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis, valued for its defined stereochemistry and purity. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the creation of novel active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds and azafluorene derivatives.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and catalysts.

Basic Information

Product Name	1-Methyl-9-Hydroxy-1,2,3,9A-Tetrahydro-1-Azafluorene Hydrochloride
CAS No.	80276-06-8
Molecular Formula	C₁₃H₁₅NO·HCl
Molecular Weight	237.72 g/mol
Synonyms	9-Hydroxy-1-methyl-1,2,3,9a-tetrahydro-1-azafluorene hydrochloride; 1-Methyl-1,2,3,9a-tetrahydro-9H-1-azafluoren-9-ol hydrochloride; Tetrahydroazafluorenol hydrochloride derivative; 1-Azafluorene hydrochloride derivative; 1-Methyl-9-azafluorenol HCl; 80276-06-8 (CAS); 1-Methyl-9-hydroxy-1,2,3,9a-tetrahydro-1H-1-azafluorene hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-9-Hydroxy-1,2,3,9A-Tetrahydro-1-Azafluorene Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.