Description

Sodium 3-Mercapto-2-Methylpropionate is the sodium salt derivative of 3-mercapto-2-methylpropionic acid, a versatile organosulfur compound. This chemical is valued for its ability to act as a sulfur-based nucleophile and chain transfer agent, making it crucial for controlling polymer molecular weight and introducing functional thiol groups. It is primarily sought by industries involved in specialty polymer synthesis, pharmaceutical intermediates, and fine chemical manufacturing where precise molecular architecture is required.

Application

• Polymer Industry: As a chain transfer agent (CTA) in free-radical polymerization (e.g., acrylics, styrenics) to control molecular weight and polydispersity.
• Pharmaceutical Synthesis: As a key intermediate or building block for introducing thiol functionality into active pharmaceutical ingredients (APIs) and drug candidates.
• Fine Chemical Production: Utilized in the synthesis of complex organic molecules, ligands, and catalysts that require a protected or latent thiol group.
• Surface Modification: For creating self-assembled monolayers (SAMs) or functionalizing surfaces with thiol groups for subsequent conjugation.
• Bioconjugation Chemistry: Acting as a linker or reagent for modifying proteins, peptides, or other biomolecules via thiol-maleimide or disulfide bond formation.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	Sodium 3-Mercapto-2-Methylpropionate
CAS No.	80224-20-0
Molecular Formula	C4H7NaO2S
Molecular Weight	142.15 g/mol
Synonyms	3-Mercapto-2-methylpropionic acid sodium salt; Sodium 3-mercaptoisobutyrate; 2-Methyl-3-sulfanylpropanoic acid sodium salt; Sodium 2-methyl-3-mercaptopropionate; 3-Mercapto-2-methylpropanoic acid sodium salt; MMP-Sodium salt; Sodium MMP; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Sodium 3-Mercapto-2-Methylpropionate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay, impurity profile, and residual solvents. Specifications can be aligned with cGMP and ICH guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.