Description

Chelex is a high-purity, cross-linked polystyrene resin functionalized with iminodiacetic acid groups, widely recognized for its exceptional metal chelating properties. This product is crucial for applications requiring the selective removal or purification of transition metal ions from complex solutions. It is an essential material for researchers and manufacturers in biochemistry, molecular biology, pharmaceutical development, and industrial water treatment.

Application

• Protein Purification: Removal of metal ions to prevent enzyme inhibition or for the purification of metalloproteins.
• Molecular Biology: Chelation of divalent cations (e.g., Mg²⁺, Ca²⁺) to inactivate nucleases and protect nucleic acids during extraction and storage.
• Buffer & Reagent Preparation: De-metallization of buffers, solutions, and growth media for sensitive biochemical assays and cell culture.
• Pharmaceutical Intermediates: Scavenging of metal catalyst residues during the synthesis of active pharmaceutical ingredients (APIs).
• Analytical Chemistry: Sample preparation for trace metal analysis by techniques like ICP-MS or AAS.
• Industrial Process Water: Selective removal of heavy metal contaminants from wastewater streams.
• Laboratory Scale Chromatography: Used in column chromatography for the separation of metal-binding compounds.

Basic Information

Product Name	Chelex
CAS No.	80208-96-4
Molecular Formula	(C9H9NO4·Na)n
Molecular Weight	~218.16 (monomer unit, sodium form)
Synonyms	Chelex 100; Iminodiacetic acid, sodium salt, polymer-bound; Chelating resin (iminodiacetate); Polystyrene-iminodiacetic acid resin; Chelating ion exchange resin; Bio-Rad Chelex; Chelating adsorbent; Sodium poly(styrene-co-divinylbenzene-iminodiacetate)
EINECS	Contact for details

Quality Control

Our Chelex resin is manufactured under a strict quality management system. Each lot undergoes rigorous testing to ensure consistent performance, including assessment of chelating capacity, particle size distribution, and chemical stability. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15-25°C) in a dry, well-ventilated area. The resin is supplied in a slurry; avoid letting it dry out completely. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white beads
Matrix	Polystyrene-DVB
Functional Group	Iminodiacetic acid, sodium form
Ionic Form (as shipped)	Na⁺
Capacity (min.)	0.4 meq/mL
Particle Size Range	75-150 μm (100-200 mesh)
Moisture Content	50-60% (in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.