Description

(1,1-Dimethylethyl)Dimethyl[(1-Methyl-3-Butynyl)Oxy]Silane is a specialized organosilicon compound, specifically a silyl-protected alkyne derivative. This chemical is valued for its role as a versatile building block and protecting group in advanced organic synthesis, particularly in the development of pharmaceuticals and complex organic materials. It is essential for researchers and manufacturers in the fine chemical, pharmaceutical, and material science industries who require high-purity intermediates for coupling reactions and polymer modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing alkyne functionalities via cross-coupling reactions like Sonogashira.
• Organic Synthesis Building Block: Used as a protected alkyne reagent in multi-step synthetic routes for complex natural products and novel organic compounds.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of specialty silicones and advanced polymeric materials.
• Agrochemical Synthesis: Employed in the research and production of advanced crop protection agents and herbicides.
• Surface Modification & Coatings: Acts as a coupling agent or surface modifier to alter the properties of inorganic materials like glass or silica.
• Research & Development: A critical reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating molecular libraries.

Basic Information

Product Name	(1,1-Dimethylethyl)Dimethyl[(1-Methyl-3-Butynyl)Oxy]Silane
CAS No.	80186-44-3
Molecular Formula	C9H18OSi
Molecular Weight	170.32 g/mol
Synonyms	tert-Butyldimethyl[(1-methyl-3-butynyl)oxy]silane; 1-Methyl-3-butynyloxy-tert-butyldimethylsilane; (1-Methyl-3-butynyloxy)-tert-butyldimethylsilane; TBDMS ether of 1-Methyl-3-butyn-1-ol; tert-Butyl((1-methylbut-3-yn-1-yl)oxy)dimethylsilane; 3-Butyn-1-ol, 1-methyl-, 1-(1,1-dimethylethyl)dimethylsilyl ether; Silane, (1,1-dimethylethyl)dimethyl[(1-methyl-3-butynyl)oxy]-
EINECS	Contact for details

Quality Control

Our (1,1-Dimethylethyl)Dimethyl[(1-Methyl-3-Butynyl)Oxy]Silane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.