Description

1,2-Propanediol-D8 is a deuterated analog of propylene glycol, where eight hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This high isotopic purity makes it an essential internal standard and tracer in advanced analytical chemistry, particularly for mass spectrometry and nuclear magnetic resonance (NMR) studies. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise quantification and metabolic pathway analysis.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS, LC-MS, and NMR for the accurate quantification of propylene glycol and related compounds in complex matrices.
• Metabolic Tracer Studies: Enables the tracking of biochemical pathways and metabolic fate in pharmaceutical and nutritional research.
• Deuterated Solvent for Spectroscopy: Serves as a solvent or co-solvent in NMR spectroscopy to avoid signal interference from protonated solvents.
• Chemical Synthesis Intermediate: Employed in the synthesis of deuterium-labeled fine chemicals, active pharmaceutical ingredients (APIs), and specialty polymers.
• Quality Control & Method Development: Critical for developing and validating analytical methods in regulatory environments (e.g., FDA, EMA).
• Material Science Research: Used in studies of polymer dynamics, diffusion processes, and formulation stability where isotopic labeling is required.

Basic Information

Product Name	1,2-Propanediol-D8
CAS No.	80156-55-4
Molecular Formula	C3D8O2
Molecular Weight	88.15 g/mol
Synonyms	Propylene Glycol-d8; [2H8]-1,2-Propanediol; 1,2-Dideuteriooxy-1,1,2,3,3,3-hexadeuteriopropane; Deuterated Propylene Glycol; (2H8)Propane-1,2-diol; 1,2-Propanediol (octadeutero); PG-d8
EINECS	Contact for details

Quality Control

Our 1,2-Propanediol-D8 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity by GC or HPLC, and residual solvent content. We adhere to cGMP principles for laboratory chemicals, ensuring traceability, consistency, and reliability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.