Description

3-(3-Chlorophenyl)Prop-2-Yn-1-Ol CAS NO 80151-33-3 is a versatile organic building block featuring both a terminal alkyne and a chlorinated aromatic ring, making it a valuable intermediate for advanced synthesis. Its molecular structure is prized for enabling efficient cross-coupling reactions and serving as a precursor to more complex heterocyclic compounds. This chemical is essential for R&D and production in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Organic Synthesis: A crucial building block for Sonogashira, Click Chemistry, and other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe & Dye Precursor: Used in the synthesis of organic chromophores and fluorescent markers for bio-imaging.

Basic Information

Product Name	3-(3-Chlorophenyl)Prop-2-Yn-1-Ol
CAS No.	80151-33-3
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	3-(3-Chlorophenyl)-2-propyn-1-ol; 3-(3-Chlorophenyl)propiolic alcohol; 3-Chlorophenyl propargyl alcohol; 1-(3-Chlorophenyl)-2-propyn-1-ol; m-Chlorophenylpropynol; 3-Chloro-α-(prop-2-yn-1-yl)benzyl alcohol; 80151-33-3; 3-(3-Chlorophenyl)prop-2-yn-1-ol
EINECS	Contact for details

Quality Control

Our production of 3-(3-Chlorophenyl)Prop-2-Yn-1-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.