Description

5-Bromo-3-Methyl-8-Nitroisoquinoline (Wx130491) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring bromo, methyl, and nitro substituents on the isoquinoline core, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for targeting various enzyme families and receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty dyes or pigments.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis: A key starting material for the contract manufacturing of bespoke, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	5-Bromo-3-Methyl-8-Nitroisoquinoline (Wx130491)
CAS No.	80066-67-7
Molecular Formula	C10H7BrN2O2
Molecular Weight	267.08 g/mol
Synonyms	8-Nitro-5-bromo-3-methylisoquinoline; 3-Methyl-5-bromo-8-nitroisoquinoline; 5-Bromo-3-methyl-8-nitro-isoquinoline; Isoquinoline, 5-bromo-3-methyl-8-nitro-; WX-130491; WX130491
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-8-Nitroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.