Description

(R)-1-(3-Chlorophenyl)-1,2-Ethanediol CAS NO 80051-04-3 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry and functional group arrangement make it a critical precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel therapeutic agents and specialty products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands for transition metal catalysis and organocatalysts.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	(R)-1-(3-Chlorophenyl)-1,2-Ethanediol
CAS No.	80051-04-3
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	(R)-3-Chlorophenylethane-1,2-diol; (R)-1-(3-Chlorophenyl)ethane-1,2-diol; (R)-3-Chloromandelic Alcohol; (R)-3-Chloro-α,β-dihydroxyethylbenzene; (R)-1-(3-Chlorophenyl)-1,2-dihydroxyethane; (R)-3-Chlorophenylglycol; (R)-3-CPED; (R)-Enantiomer of 1-(3-Chlorophenyl)ethane-1,2-diol
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Chlorophenyl)-1,2-Ethanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for identity, assay, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.