Description

2-(2,5-Dioxopyrrolidin-1-Yl)Benzoic Acid is a versatile heterocyclic benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a maleimide-like moiety, makes it an essential reagent for creating amide bonds and functionalizing molecules under mild conditions. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring maleimide or succinimide conjugation.
• Bioconjugation Reagent: Used for site-specific labeling and crosslinking of proteins, antibodies, and peptides in biopharmaceutical development and diagnostic assays.
• Polymer Chemistry: Serves as a functional monomer or crosslinking agent for synthesizing specialty polymers with tailored properties.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the development of advanced materials, including coatings, adhesives, and functional surfaces.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-(2,5-Dioxopyrrolidin-1-Yl)Benzoic Acid
CAS No.	80022-74-8
Molecular Formula	C11H9NO4
Molecular Weight	219.19 g/mol
Synonyms	1-(2-Carboxyphenyl)-2,5-pyrrolidinedione; 2-(2,5-Dioxo-1-pyrrolidinyl)benzoic acid; N-(2-Carboxyphenyl)maleimide; 2-(1,3-Dioxo-2,5-pyrrolidinediyl)benzoic Acid; 2-(2,5-Dioxopyrrolidin-1-yl)benzoic acid; Benzoic acid, 2-(2,5-dioxo-1-pyrrolidinyl)-; N-(o-Carboxyphenyl)maleimide
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dioxopyrrolidin-1-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.