Description

Horse Chestnut, Aesculus Hippocastanum, Ext. is a standardized botanical extract derived from the seeds of the *Aesculus hippocastanum* tree, valued for its high concentration of bioactive saponins, primarily aescin. This natural extract is a critical ingredient for formulators seeking clinically-backed, plant-based solutions for vascular health and topical applications. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and personal care industries.

Application

• Pharmaceutical Formulations: Used in oral and topical medications for chronic venous insufficiency (CVI), varicose veins, and hemorrhoids due to its venotonic and anti-inflammatory properties.
• Dietary Supplements & Nutraceuticals: Incorporated into capsules, tablets, and tinctures aimed at supporting circulatory health, reducing leg swelling, and improving capillary integrity.
• Topical Cosmeceuticals: A key active in creams, gels, and serums designed to reduce under-eye puffiness, dark circles, and the appearance of spider veins.
• Sports & Wellness Products: Formulated into gels and balms for post-exercise recovery to alleviate muscle soreness and reduce swelling.
• Veterinary Applications: Used in animal health products for similar anti-edema and circulatory support benefits.

Basic Information

Product Name	Horse Chestnut, Aesculus Hippocastanum, Ext.
CAS No.	8053-39-2
Molecular Formula	Not Applicable (Complex Botanical Extract)
Molecular Weight	Not Applicable
Synonyms	Aesculus hippocastanum extract; Horse Chestnut Seed Extract; Aescin; Escin; Venostasin; Hippocastani semen extract; Venoplant; Reparil
EINECS	Contact for details

Quality Control

Our Horse Chestnut Extract is produced under strict quality management systems. Each batch is standardized to a defined aescin content (typically 16-20% or as specified) and undergoes comprehensive testing for identity, purity, and potency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing assay results, heavy metals, microbial limits, and residual solvents in compliance with relevant pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or heat should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Fine brownish-yellow powder
Identification (HPLC/TLC)	Complies
Assay (Aescin Content)	Min. 16% (Customizable to 20% or higher)
Loss on Drying	≤ 5.0%
Ash	≤ 5.0%
Heavy Metals (as Pb)	≤ 10 ppm
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.