Description

Digitalis (3 G) CAS NO 8031-42-3 is a standardized botanical extract derived from the leaves of the *Digitalis purpurea* (foxglove) plant, serving as a critical source of cardiac glycosides. This product is essential for its role in the research and development of cardiovascular therapeutics, providing the foundational active principles for pharmacological studies. It is primarily required by pharmaceutical manufacturers, research institutions, and biotechnology companies engaged in drug discovery, formulation development, and quality control of heart medications.

Application

• Pharmaceutical Active Ingredient: Serves as the primary raw material for the isolation and purification of cardiac glycosides like digoxin and digitoxin.
• Reference Standard: Used as a qualitative and quantitative standard in analytical laboratories for HPLC, TLC, and spectrophotometric assays of digitalis-based drugs.
• Biomedical Research: Employed in preclinical studies to investigate the mechanisms of action, pharmacokinetics, and toxicology of cardiac glycosides.
• Formulation Development: Utilized in the development and testing of solid dosage forms (tablets, capsules) and injectable formulations.
• Traditional Medicine Standardization: Acts as a benchmark for standardizing herbal preparations that utilize digitalis extracts.
• Educational Purposes: Supplied to academic institutions for teaching pharmacology and phytochemistry.

Basic Information

Product Name	Digitalis (3 G)
CAS No.	8031-42-3
Molecular Formula	Not applicable (Complex botanical extract)
Molecular Weight	Not applicable
Synonyms	Digitalis Leaf Powder; Foxglove Leaf; Digitalis Purpurea Leaf; Digitalis Folium; Digitalis Preparation; Digitalis Extract; Cardiac Glycosides Extract; Digitals
EINECS	232-420-1

Quality Control

Our Digitalis (3 G) is produced and tested to ensure it meets stringent quality parameters suitable for pharmaceutical research. Each batch is analyzed for key markers including total cardiac glycoside content, identity, and purity. Certificates of Analysis (COA) documenting assay results, heavy metals, microbial limits, and residual solvents are available upon request, supporting compliance with cGMP and relevant pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Description	Fine, greenish-brown powder with characteristic odor
Identification (TLC)	Conforms to standard
Assay (Total Glycosides)	≥ 3.0% (as digitoxin)
Loss on Drying	≤ 5.0%
Ash Content	≤ 12.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.