Description

Belladonna Extract is a standardized botanical preparation derived from the *Atropa belladonna* plant, known for its content of tropane alkaloids such as atropine and scopolamine. This extract is valued for its precise pharmacological activity and consistent quality, making it a critical intermediate for the production of various therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers, research institutions, and developers of botanical drug products seeking a reliable and well-characterized active ingredient.

Application

• Pharmaceutical Intermediates: Serves as a key starting material for the synthesis and standardization of anticholinergic and antispasmodic medications.
• Antispasmodic Formulations: Used in the development of drugs aimed at relieving gastrointestinal cramps, irritable bowel syndrome (IBS), and biliary colic.
• Ophthalmic Solutions: Employed in the production of mydriatic (pupil-dilating) agents for eye examinations and surgeries.
• Analgesic Adjuncts: Incorporated into formulations designed to manage pain, particularly visceral pain, due to its smooth muscle relaxant properties.
• Research & Development: Used as a reference standard and active component in pharmacological, toxicological, and botanical research studies.
• Veterinary Medicine: Applied in veterinary pharmaceuticals for its antispasmodic and antisecretory effects in animals.

Basic Information

Product Name	Belladonna Extract
CAS No.	8027-38-1
Molecular Formula	Complex Botanical Extract
Molecular Weight	N/A (Standardized by Alkaloid Content)
Synonyms	Deadly Nightshade Extract; Atropa Belladonna Extract; Belladonna Leaf Extract; Belladonna Herb Extract; Belladonnae Folii Extractum; Belladonnae Herba Extract; Belladonna Tincture (concentrated); Belladonna Dry Extract
EINECS	Contact for details

Quality Control

Our Belladonna Extract is manufactured under strict quality management systems. Each batch is rigorously tested to ensure compliance with relevant pharmacopoeial standards such as USP, EP, or customer-specific monographs. Key quality attributes, including alkaloid content (typically atropine and scopolamine), purity, and residual solvents, are verified. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere for long-term stability. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Brown to greenish-brown powder or extract
Identification (TLC/HPLC)	Complies
Assay (Total Alkaloids)	0.95% - 1.05% (as atropine) or as specified
Atropine Content (HPLC)	Specified range
Scopolamine Content (HPLC)	Specified range
Loss on Drying	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Total Aerobic Microbial Count	≤ 10³ CFU/g
Total Yeast & Mold Count	≤ 10² CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.