Description

Methyl(Triphenyl)Phosphonium Chloride is a versatile and highly reactive organophosphorus salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stable ylide precursor for the Wittig reaction, enabling the efficient synthesis of alkenes from carbonyl compounds. This makes it an indispensable material for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Wittig Olefination: The principal application is as a precursor to the methylenetriphenylphosphorane ylide for converting aldehydes and ketones into terminal alkenes (methylene compounds).
• Pharmaceutical Intermediates: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring specific alkene functionalities.
• Agrochemical Synthesis: Employed in creating key intermediates for herbicides, fungicides, and plant growth regulators.
• Material Science: Facilitates the production of specialty monomers and polymers, including those used in liquid crystals and organic electronics.
• Fine Chemical Production: Serves as a building block in the multi-step synthesis of flavors, fragrances, and dyes.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research and process optimization for novel organic transformations.

Basic Information

Product Name	Methyl(Triphenyl)Phosphonium Chloride
CAS No.	896-33-3
Molecular Formula	C19H18ClP
Molecular Weight	312.77 g/mol
Synonyms	Methyltriphenylphosphonium chloride; (Methyl)triphenylphosphonium chloride; Phosphonium, methyltriphenyl-, chloride; Triphenylmethylphosphonium chloride; MTPP-Cl; Methyltriphenylphosphorus chloride; NSC 5111; Methyl(triphenyl)phosphanium chloride
EINECS	212-984-2

Quality Control

Our Methyl(Triphenyl)Phosphonium Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by titration or HPLC), identity confirmation (by IR and NMR), and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	~230°C (dec.)
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility	Soluble in polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.