Description

3-Bromothiophene is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its primary value lies in enabling the introduction of the bromine atom for subsequent cross-coupling reactions, facilitating the construction of complex molecular architectures. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediates: A key synthon for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiophene moiety contributes to biological activity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, enhancing reaction selectivity and efficiency.
• Chemical Research & Development: A fundamental reagent for exploring new synthetic methodologies, including Suzuki, Stille, and Negishi cross-coupling reactions.
• Functional Dyes and Pigments: Acts as a building block for creating novel chromophores with specific light-absorption and emission properties.

Basic Information

Product Name	3-Bromothiophene
CAS No.	872-31-1
Molecular Formula	C4H3BrS
Molecular Weight	163.03 g/mol
Synonyms	3-Bromothiophene; β-Bromothiophene; Thiophene, 3-bromo-; 3-Thienyl bromide; NSC 404083; 3-Bromo-thiophene; 3-Bromothiofuran; 872-31-1
EINECS	212-824-5

Quality Control

Our 3-Bromothiophene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and reproducible performance in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile and light-sensitive nature, it is recommended to store at controlled room temperature (15-25°C) under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.72 g/mL
Refractive Index (n20D)	~1.588

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.