Description

Difluorotriphenylphosphorane is a versatile organophosphorus reagent, specifically a fluorinating agent, widely recognized in synthetic organic chemistry. Its primary value lies in its ability to facilitate the conversion of alcohols and carbonyl compounds to the corresponding alkyl and gem-difluoro olefins, respectively, making it a critical tool for introducing fluorine atoms into complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is required to modulate the biological activity, stability, and physical properties of target compounds.

Application

• Key reagent for the deoxyfluorination of alcohols to synthesize alkyl fluorides.
• Used in the conversion of aldehydes and ketones to gem-difluoroalkenes, a valuable transformation in medicinal chemistry.
• Employed as a fluorinating agent in nucleophilic substitution reactions for the synthesis of fluorinated building blocks.
• Facilitates the synthesis of fluorinated analogs of bioactive molecules for drug discovery and development.
• Applied in materials science for the preparation of fluorinated monomers and polymers with unique properties.
• Utilized in agrochemical research to create fluorinated pesticides and herbicides with enhanced efficacy.

Basic Information

Product Name	Difluorotriphenylphosphorane
CAS No.	845-64-7
Molecular Formula	C18H15F2P
Molecular Weight	300.28 g/mol
Synonyms	Triphenyldifluorophosphorane; Difluorotriphenylphosphorus; (Difluorophosphoranyl)benzene; P,P-Difluoro-P,P,P-triphenylphosphorane; Phosphorane, difluorotriphenyl-; NSC 163082; EINECS 212-672-2
EINECS	212-672-2

Quality Control

Our Difluorotriphenylphosphorane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from incompatible materials such as strong oxidizers and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.