Description

Sodium 1,2,3,6-Tetrahydro-1,3-Dimethyl-2,6-Dioxo-7H-Purine-7-Acetate is a high-purity, water-soluble xanthine derivative salt, essential for precise formulation in advanced pharmaceutical and research applications. This compound serves as a critical synthetic intermediate and active pharmaceutical ingredient (API) building block, valued for its consistent quality and reliable performance. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical producers engaged in the development of central nervous system (CNS) agents, respiratory stimulants, and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of theophylline derivatives and other xanthine-based active pharmaceutical ingredients (APIs).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production of medications targeting respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).
• Biochemical Research: Serves as a standard or reagent in studies involving adenosine receptor antagonism and phosphodiesterase (PDE) inhibition pathways.
• Fine Chemical Synthesis: Employed as a specialized intermediate for creating novel compounds in medicinal chemistry and drug discovery programs.
• Reference Standard: Used in analytical laboratories for quality control (QC) and method development via HPLC or other chromatographic techniques.

Basic Information

Item	Details
Product Name	Sodium 1,2,3,6-Tetrahydro-1,3-Dimethyl-2,6-Dioxo-7H-Purine-7-Acetate
CAS No.	837-27-4
Molecular Formula	C9H9N4NaO4
Molecular Weight	260.19 g/mol
Synonyms	7-(Carboxymethyl)theophylline Sodium Salt; Sodium Theophylline-7-acetate; Acefylline Sodium; Theophylline-7-acetic Acid Sodium Salt; 1,3-Dimethyl-7-(sodiooxycarbonylmethyl)xanthine; Sodium 1,3-Dimethyl-2,6-dioxo-7-(carboxymethyl)-1,2,3,6-tetrahydropurine; 7-(Carboxymethyl)-1,3-dimethylxanthine Sodium Salt
EINECS	212-652-8

Quality Control

Our Sodium 1,2,3,6-Tetrahydro-1,3-Dimethyl-2,6-Dioxo-7H-Purine-7-Acetate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
pH (5% Solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.