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5-Chloroindole-3-Carboxaldehyde CAS NO 827-01-0


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CAS No.:827-01-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Chloroindole-3-Carboxaldehyde is a versatile and high-value halogenated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both an aldehyde and a chloro-substituted indole ring, makes it an indispensable building block for constructing complex heterocyclic compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, serotonin receptor modulators, and other biologically active indole alkaloids.
  • Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
  • Material Science Research: Used in the creation of organic semiconductors, ligands for catalysis, and novel photochromic or fluorescent materials.
  • Academic & R&D Laboratories: Fundamental reagent for methodological studies in organic synthesis, particularly in palladium-catalyzed cross-coupling and multi-component reactions.
  • Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name 5-Chloroindole-3-Carboxaldehyde
CAS No. 827-01-0
Molecular Formula C9H6ClNO
Molecular Weight 179.60 g/mol
Synonyms 5-Chloro-1H-indole-3-carboxaldehyde; 5-Chloro-3-formylindole; 3-Formyl-5-chloroindole; 5-Chloroindole-3-aldehyde; 1H-Indole-3-carboxaldehyde, 5-chloro-; NSC 403119; 5-Chloro-1H-indole-3-carbaldehyde
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Quality Control

Our 5-Chloroindole-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Off-white to pale yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point 185 - 190 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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