Description

3-Nitrothiophene is a versatile nitro-substituted heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique electronic structure makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the nitro-thiophene moiety contributes to biological activity.
• Organic Synthesis Building Block: Employed in various name reactions and coupling processes to construct complex heterocyclic systems and functionalized molecules.
• Material Science Research: Acts as a precursor for conductive polymers, organic semiconductors, and other electronic materials due to its electron-accepting properties.
• Dye and Pigment Industry: Utilized in the synthesis of specialized dyes and colorants where the nitro group influences color and stability.
• Chemical Research & Development: Serves as a standard reagent in academic and industrial R&D labs for method development and exploratory synthesis.

Basic Information

Product Name	3-Nitrothiophene
CAS No.	822-84-4
Molecular Formula	C4H3NO2S
Molecular Weight	129.14 g/mol
Synonyms	3-Nitrothiophene; Thiophene, 3-nitro-; 3-Nitro-thiophene; Nitrothiophene; 3-NT; 3-Nitrothiofene; β-Nitrothiophene; NSC 404087
EINECS	212-518-9

Quality Control

Our 3-Nitrothiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting a purity specification of ≥98.0% (HPLC). Each batch is accompanied by a detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles. Our quality control protocols are designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	76 - 80 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.