Description

Methanol-D4 CAS NO 811-98-3 is a deuterated isotopologue of methanol, where four hydrogen atoms are replaced by deuterium, resulting in a molecular formula of CD₄O. This high isotopic purity compound is an essential tool in advanced analytical chemistry, providing a stable, non-exchangeable deuterium source for precise spectroscopic and mechanistic studies. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, chemical, and academic sectors for applications such as NMR spectroscopy, mass spectrometry, and reaction mechanism elucidation.

Application

• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a critical deuterated solvent for locking and shimming NMR spectrometers, enabling high-resolution structural analysis of organic molecules.
• Mass Spectrometry (MS): Used as a reagent or matrix in various MS techniques, including chemical ionization, for accurate mass determination and fragmentation studies.
• Reaction Mechanism Studies: Acts as a deuterium-labeling agent to trace reaction pathways, hydrogen/deuterium exchange kinetics, and isotope effects in chemical and biochemical reactions.
• Pharmaceutical Research & Development: Employed in the synthesis of deuterated drug candidates (deuterated pharmaceuticals) to potentially improve metabolic stability and pharmacokinetic profiles.
• Analytical Reference Standard: Functions as a high-purity internal standard or reference material in quantitative analytical methods to ensure accuracy and reproducibility.
• Material Science Research: Utilized in the development and analysis of novel materials, including organic electronics and polymers, where deuterium labeling provides unique insights.

Basic Information

Item	Detail
Product Name	Methanol-D4
CAS No.	811-98-3
Molecular Formula	CD₄O
Molecular Weight	36.07 g/mol
Synonyms	Deuterated Methanol; Methanol-d4; Tetradeuteromethanol; [²H₄]Methanol; Methyl Alcohol-d4; Perdeuteromethanol; CD₃OD; Deuteromethanol
EINECS	Contact for details

Quality Control

Our Methanol-D4 is produced and tested under stringent quality management protocols to ensure exceptional isotopic and chemical purity, meeting the exacting requirements of research and analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity by NMR and GC, and residual solvent/water content. We adhere to relevant industry standards for high-purity reagents, and custom specifications for specific research or GMP applications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is between 2°C and 25°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Isotopic Purity (D atom %)	≥ 99.8%
Chemical Purity (by NMR)	≥ 99.5%
Water Content (KF)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.