Description

(R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is a high-purity chiral tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological intermediate and a versatile building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in neurological and cardiovascular drug discovery programs, where its specific stereochemistry is essential for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents targeting neurological receptors.
• Alkaloid Research: Used as a reference standard and synthetic target in the study of tetrahydroisoquinoline alkaloids and their biological properties.
• Asymmetric Synthesis: Employed as a building block in complex, stereoselective organic reactions to construct molecules with defined three-dimensional structures.
• Medicinal Chemistry R&D: Utilized in structure-activity relationship (SAR) studies to optimize drug candidates for potency and selectivity.
• Chemical Biology: Acts as a probe or ligand in biochemical assays to study enzyme interactions and signal transduction pathways.

Basic Information

Product Name	(R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	85-63-2
Molecular Formula	C21H27NO4
Molecular Weight	357.45 g/mol
Synonyms	(R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
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Quality Control

Our (R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.