Description

(S)-(-)-Indoline-2-Carboxylicacid CAS NO 799815-20-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key precursor for the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed reactions to produce enantiomerically pure compounds.
• Agrochemical Synthesis: Serves as a building block for developing advanced, stereospecific pesticides and herbicides.
• Peptidomimetics Research: Employed in medicinal chemistry for constructing constrained peptide analogs and protease inhibitors.
• Natural Product Synthesis: A valuable starting material for the total synthesis of complex natural products containing the indoline scaffold.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(S)-(-)-Indoline-2-Carboxylicacid
CAS No.	799815-20-6
Molecular Formula	C9H9NO2
Molecular Weight	163.18 g/mol
Synonyms	(S)-Indoline-2-carboxylic acid; (2S)-2,3-Dihydro-1H-indole-2-carboxylic acid; L-Indoline-2-carboxylic acid; (S)-2-Carboxyindoline; (-)-Indoline-2-carboxylic acid; (S)-2,3-Dihydro-1H-indole-2-carboxylic acid; (S)-1,2,3,4-Tetrahydro-2-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-(-)-Indoline-2-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.