Description

5-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, enzyme inhibitors, and tool compounds for biological target validation.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, such as ligands for catalysis or components for organic electronics.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting exploratory research in medicinal and synthetic chemistry.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for fluorinated isoquinoline derivatives.

Basic Information

Product Name	5-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	799274-07-0
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	5-Fluoro-1,2,3,4-tetrahydroisoquinoline HCl; 5-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 5-Fluoro-THIQ hydrochloride; 5-F-THIQ HCl; 1,2,3,4-Tetrahydro-5-fluoroisoquinoline hydrochloride; 5-Fluoro-3,4-dihydro-1H-isoquinoline hydrochloride; 5-Fluoro-1,2,3,4-tetrahydroisoquinolinium chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict internal quality management protocols to ensure reliable and reproducible material for your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.