Description

1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,Hydrochloride (1:1) is a high-purity, chemically defined intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel therapeutic agents, particularly those targeting the central nervous system.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with specific modes of action.
• Organic Synthesis Reagent: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and isoquinoline derivatives.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: Potential intermediate for creating specialized organic ligands or functional polymers.

Basic Information

Product Name	1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,Hydrochloride (1:1)
CAS No.	799274-03-6
Molecular Formula	C₁₃H₁₇NO₂·HCl
Molecular Weight	255.74 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-1-isoquinolineacetate hydrochloride; 1,2,3,4-Tetrahydroisoquinoline-1-acetic acid methyl ester hydrochloride; Methyl (1,2,3,4-tetrahydro-1-isoquinolyl)acetate hydrochloride; 1-Carbomethoxymethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; THIQ-AA-Me ester HCl; (1,2,3,4-Tetrahydro-1-isoquinolinyl)acetic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,Hydrochloride (1:1) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and provided upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.