Description

3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride is a high-purity, synthetically valuable organic building block. This compound is significant for its rigid, three-dimensional bicyclo[1.1.1]pentane (BCP) scaffold, which is increasingly used in medicinal chemistry to improve the physicochemical and pharmacokinetic properties of drug candidates. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for incorporating the bicyclo[1.1.1]pentane motif into drug discovery programs, particularly for CNS and metabolic disease targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to replace aromatic rings or tert-butyl groups, reducing lipophilicity and improving metabolic stability.
• Agrochemical Research: Serves as a rigid spacer or bioisostere in the development of new pesticides and herbicides.
• Chemical Biology: Utilized as a probe or linker in chemical biology to study protein-ligand interactions due to its unique spatial geometry.
• Material Science Research: Potential precursor for novel polymers or advanced materials requiring rigid, three-dimensional molecular components.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis for clients.

Basic Information

Product Name	3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride
CAS No.	796963-34-3
Molecular Formula	C7H14ClN
Molecular Weight	147.64 g/mol
Synonyms	1-Amino-3-methylbicyclo[1.1.1]pentane hydrochloride; 3-Methyl-BCP-amine HCl; 3-Methylbicyclo[1.1.1]pentan-1-amine HCl; 3-Methyl-1-aminobicyclo[1.1.1]pentane hydrochloride; Bicyclo[1.1.1]pentan-1-amine, 3-methyl-, hydrochloride; 3-Methyl-BCP-NH2•HCl
EINECS	Contact for details

Quality Control

Our 3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.