Description

4-[4-(Difluoromethoxy)Phenyl]-5-Methyl-1,3-Thiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole core and difluoromethoxy phenyl substitution. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas, offering researchers a reliable building block for drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate sophisticated heterocyclic structures into their molecular designs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probes: Serves as a core scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Material Science: Potential precursor for specialty polymers or organic electronic materials due to its aromatic and heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-[4-(Difluoromethoxy)Phenyl]-5-Methyl-1,3-Thiazol-2-Amine
CAS No.	794578-70-4
Molecular Formula	C11H10F2N2OS
Molecular Weight	256.27 g/mol
Synonyms	2-Amino-4-[4-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazole; 5-Methyl-4-[4-(difluoromethoxy)phenyl]-1,3-thiazol-2-amine; 4-(4-(Difluoromethoxy)phenyl)-5-methylthiazol-2-amine; 794578-70-4; DFMP-MTA; Thiazole amine derivative CAS 794578-70-4
EINECS	Contact for details

Quality Control

Every batch of 4-[4-(Difluoromethoxy)Phenyl]-5-Methyl-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.