Description

2-Azabicyclo[2.2.1]Heptane,5-(4-Fluorophenyl)-,(1R,4R,5R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold and specific stereochemistry make it a valuable chiral intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Research: Used as a building block for creating new pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in enantioselective catalysis.
• Medicinal Chemistry Scaffold: Its constrained bicyclic structure is exploited in fragment-based drug design and for exploring novel pharmacophores.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptane,5-(4-Fluorophenyl)-,(1R,4R,5R)-Rel-(9Ci)
CAS No.	794533-85-0
Molecular Formula	C12H14FN
Molecular Weight	191.25 g/mol
Synonyms	(1R,4R,5R)-5-(4-Fluorophenyl)-2-azabicyclo[2.2.1]heptane; rel-(1R,4R,5R)-5-(4-Fluorophenyl)-2-azabicyclo[2.2.1]heptane; 5-(4-Fluorophenyl)-2-azabicyclo[2.2.1]heptane, (1R,4R,5R)-rel-; 2-Azabicyclo[2.2.1]heptane, 5-(4-fluorophenyl)-, (1R,4R,5R)-rel-; Bicyclic Fluorophenyl Amine Intermediate; (1R,4R,5R)-rel-5-(p-Fluorophenyl)-2-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.1]Heptane,5-(4-Fluorophenyl)-,(1R,4R,5R)-Rel-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.