Description

Ethyl (1S,2R,3S,4S,5S)-2,3-o-(Isopropylidene)-4-Hydroxybicyclo[3.1.0]Hexanecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined bicyclic structure. This compound is of critical importance for the synthesis of complex bioactive molecules, particularly in antiviral and anticancer research, where precise stereochemistry is essential for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and process chemistry.

Application

• Key Intermediate in Antiviral Drug Synthesis: Serves as a crucial building block in the research and production of nucleoside analogue-based antiviral medications.
• Chiral Building Block for Medicinal Chemistry: Used in the asymmetric synthesis of complex molecules for oncology and other therapeutic areas requiring specific stereochemistry.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs) at pilot and commercial scales.
• Academic & Industrial Research: Utilized in chemical biology and drug discovery programs to explore new chemical entities and their structure-activity relationships.
• Synthesis of Prodrugs: Acts as a precursor for prodrug strategies aimed at improving the pharmacokinetic properties of therapeutic compounds.

Basic Information

Item	Details
Product Name	Ethyl (1S,2R,3S,4S,5S)-2,3-o-(Isopropylidene)-4-Hydroxybicyclo[3.1.0]Hexanecarboxylate
CAS No.	793695-59-7
Molecular Formula	C13H20O5
Molecular Weight	256.30 g/mol
Synonyms	(1S,2R,3S,4S,5S)-Ethyl 2,3-O-Isopropylidene-4-hydroxybicyclo[3.1.0]hexane-1-carboxylate; Ethyl 2,3-O-Isopropylidene-4-hydroxybicyclo[3.1.0]hexane-1-carboxylate; Bicyclo[3.1.0]hexane-1-carboxylic acid, 2,3-O-(1-methylethylidene)-4-hydroxy-, ethyl ester, (1S,2R,3S,4S,5S)-; Ethyl 4-Hydroxy-2,3-O-isopropylidenebicyclo[3.1.0]hexane-1-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl (1S,2R,3S,4S,5S)-2,3-o-(Isopropylidene)-4-Hydroxybicyclo[3.1.0]Hexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.