Description

3-Isoquinolinecarboxylicacid,1,2,3,4-Tetrahydro-6,7-Dihydroxy-,(3R)-(9Ci) is a high-purity chiral isoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for pharmaceutical research, particularly in the development of neurologically active agents and enzyme inhibitors. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to create novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential central nervous system (CNS) targeting drugs and alkaloid-based therapeutics.
• Biochemical Research: Used as a reference standard or ligand in enzymatic studies and receptor binding assays due to its specific stereochemistry and functional groups.
• Asymmetric Synthesis: Serves as a complex starting material or scaffold for constructing molecules with defined stereocenters in medicinal chemistry programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value isoquinoline derivatives.

Basic Information

Product Name	3-Isoquinolinecarboxylicacid,1,2,3,4-Tetrahydro-6,7-Dihydroxy-,(3R)-(9Ci)
CAS No.	792898-30-7
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	(3R)-1,2,3,4-Tetrahydro-6,7-dihydroxy-3-isoquinolinecarboxylic acid; (R)-1,2,3,4-Tetrahydro-6,7-dihydroxyisoquinoline-3-carboxylic acid; 6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (3R); NSC 113927; (R)-THIQ-6,7-diol-3-COOH; (R)-6,7-Dihydroxytetrahydroisoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all critical parameters are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.