Description

Bicyclo[2.2.2]Octanone, 5-Methoxy-1,5-Dimethyl-3-(2-Propenyl)-, (1R,3S,4R,5R)- (9Ci) is a high-purity, stereochemically defined bicyclic ketone derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its complex, rigid molecular framework is engineered to impart specific three-dimensional orientation, which is essential for developing active compounds with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in areas requiring sophisticated molecular architecture. CAS NO 791854-91-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Utilized as a sophisticated chiral auxiliary or starting material in complex asymmetric catalytic reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space due to its constrained bicyclic scaffold.
• Fragrance & Flavor Chemistry: Potential use as a precursor for synthesizing novel odorants and flavorants with unique, long-lasting olfactory profiles.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal and mechanical properties derived from its rigid core.
• Agrochemical Development: Serves as a complex intermediate in the synthesis of next-generation pesticides and herbicides requiring specific stereochemistry for efficacy.

Basic Information

Product Name	Bicyclo[2.2.2]Octanone, 5-Methoxy-1,5-Dimethyl-3-(2-Propenyl)-, (1R,3S,4R,5R)- (9Ci)
CAS No.	791854-91-6
Molecular Formula	C14H22O2
Molecular Weight	222.33 g/mol
Synonyms	(1R,3S,4R,5R)-5-Methoxy-1,5-dimethyl-3-(prop-2-en-1-yl)bicyclo[2.2.2]octan-2-one; 5-Methoxy-1,5-dimethyl-3-(2-propenyl)-bicyclo[2.2.2]octan-2-one, (1R,3S,4R,5R)-; (1R,3S,4R,5R)-5-Methoxy-1,5-dimethyl-3-(prop-2-enyl)bicyclo[2.2.2]octan-2-one; Bicyclo[2.2.2]octan-2-one, 5-methoxy-1,5-dimethyl-3-(2-propenyl)-, (1R,3S,4R,5R)-; Chiral Bicyclo[2.2.2]octanone Derivative; Allyl-substituted Bicyclic Ketone
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octanone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.