Description

(R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-1,1'-Binaphthyl-2,2'-diol is a high-value, chiral binaphthyl derivative that serves as a sophisticated ligand and building block in asymmetric synthesis. Its core value proposition lies in its ability to impart exceptional enantioselectivity in catalytic reactions, which is critical for producing single-isomer active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• As a chiral ligand for transition metal-catalyzed asymmetric reactions, including hydrogenation, cross-coupling, and C-H activation.
• As a key precursor for constructing chiral catalysts used in the synthesis of enantiomerically pure pharmaceuticals.
• In the development of chiral stationary phases (CSPs) for analytical and preparative chromatography to separate enantiomers.
• As a building block for advanced materials with chiral optical properties, such as organic light-emitting diodes (OLEDs) and sensors.
• In academic and industrial R&D for exploring novel asymmetric methodologies and catalytic systems.

Basic Information

Product Name	(R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-1,1'-Binaphthyl-2,2'-diol
CAS No.	791616-62-1
Molecular Formula	C48H24F12O2
Molecular Weight	860.69 g/mol
Synonyms	(R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-BINOL; (R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-1,1'-Bi-2-naphthol; (R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-2,2'-Dihydroxy-1,1'-Binaphthyl; (R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-H8-BINOL; (R)-3,3'-Bis(Perfluoro-tert-butylphenyl)-BINOL (common misnomer); (R)-DTB-BINOL (common abbreviation); (R)-3,3'-Di(3,5-Bis(trifluoromethyl)phenyl)-BINOL; Chiral Binaphthyl Ligand 791616-62-1
EINECS	Contact for details

Quality Control

Every batch of our (R)-3,3'-Bis(3,5-Bis(Trifluoromethyl)Phenyl)-1,1'-Binaphthyl-2,2'-diol undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (ee) suitable for demanding catalytic applications. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and chiral chromatography. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.