Description

Bicyclo[2.2.2]Octanone, 6-Hydroxy-1-Methyl-, (1R,4S,6R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic ketone derivative. This compound serves as a valuable chiral building block and synthetic intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) or metabolic diseases.
• Asymmetric Synthesis: Employed as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantioselectivity.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for applications in homogeneous catalysis.
• Fine Chemical Production: Serves as a starting material for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and Industrial Research: A critical reagent for methodological studies in organic chemistry and for exploring new reaction pathways.
• Material Science Precursor: Potential use in synthesizing monomers for advanced polymers with specific structural properties.

Basic Information

Product Name	Bicyclo[2.2.2]Octanone, 6-Hydroxy-1-Methyl-, (1R,4S,6R)-Rel- (9Ci)
CAS No.	791067-76-0
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	rel-(1R,4S,6R)-6-Hydroxy-1-methylbicyclo[2.2.2]octan-2-one; (1R,4S,6R)-6-Hydroxy-1-methylbicyclo[2.2.2]octan-2-one (relative); 6-Hydroxy-1-methylbicyclo[2.2.2]octan-2-one; Bicyclo[2.2.2]octan-2-one, 6-hydroxy-1-methyl-, (1R,4S,6R)-rel-; 791067-76-0; Chiral Bicyclo[2.2.2]octanone Derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octanone, 6-Hydroxy-1-Methyl-, (1R,4S,6R)-Rel- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.