Description

6-Isoquinolinol,1,2,3,4-Tetrahydro-8-Methoxy-1,3-Dimethyl-,(1S-Cis)-(9Ci) is a chiral, substituted tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate and key building block for the development of novel active compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Synthesis: Employed in the preparation of complex, high-value specialty chemicals for various industrial applications.
• Academic & R&D: A valuable compound for methodological studies in asymmetric synthesis and medicinal chemistry research.
• Ligand & Catalyst Development: Potential use in creating chiral ligands for asymmetric catalysis.

Basic Information

Product Name	6-Isoquinolinol,1,2,3,4-Tetrahydro-8-Methoxy-1,3-Dimethyl-,(1S-Cis)-(9Ci)
CAS No.	790180-98-2
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	(1S,3S)-1,3-Dimethyl-8-methoxy-1,2,3,4-tetrahydro-6-isoquinolinol; (1S-cis)-1,2,3,4-Tetrahydro-8-methoxy-1,3-dimethyl-6-isoquinolinol; 8-Methoxy-1,3-dimethyl-1,2,3,4-tetrahydro-6-isoquinolinol (cis-1S); 6-Hydroxy-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline (1S,3S)-; THIQ derivative; Chiral tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinol,1,2,3,4-Tetrahydro-8-Methoxy-1,3-Dimethyl-,(1S-Cis)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.