Description

5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining tetramethylpiperidine and thiophene moieties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials, offering a versatile building block for medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Functions as a building block for creating new active ingredients in crop protection and pesticide formulations.
• Functional Material Synthesis: Employed in the development of organic electronic materials, ligands for catalysis, and specialty polymers.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic Acid
CAS No.	788811-22-3
Molecular Formula	C14H19NO2S
Molecular Weight	265.37 g/mol
Synonyms	5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydropyridin-4-yl)thiophene-2-carboxylic acid; 4-(5-Carboxythiophen-2-yl)-2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridine; 2-Thiophenecarboxylic acid, 5-(2,2,6,6-tetramethyl-1,2,3,6-tetrahydro-4-pyridinyl)-; TMT-Thiophene Acid; CAS 788811-22-3
EINECS	Contact for details

Quality Control

Our production of 5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.