Description

1-(4-Chloro-7-(Phenylsulfonyl)Isoquinolin-1-Yl)Guanidine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation small molecule drugs and for process optimization studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other bioactive molecules.
• Oncology Research: Used in the development of novel anti-cancer compounds targeting specific cellular pathways.
• Antiviral Drug Development: Serves as a core scaffold for creating potential antiviral agents.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and receptor binding.
• Process Chemistry & Scale-Up: Utilized for route scouting, optimization, and pilot-scale production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1-(4-Chloro-7-(Phenylsulfonyl)Isoquinolin-1-Yl)Guanidine
CAS No.	788807-49-8
Molecular Formula	C₁₆H₁₃ClN₄O₂S
Molecular Weight	360.82 g/mol
Synonyms	1-(4-Chloro-7-(phenylsulfonyl)isoquinolin-1-yl)guanidine; Guanidine, N-[4-chloro-7-(phenylsulfonyl)-1-isoquinolinyl]-; 788807-49-8; 4-Chloro-7-(phenylsulfonyl)-1-isoquinolinamine, N-cyano-; N-(4-Chloro-7-(phenylsulfonyl)isoquinolin-1-yl)guanidine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-7-(Phenylsulfonyl)Isoquinolin-1-Yl)Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.