Description

Ethyl 4-Bromobenzoate D4 is a deuterated isotopologue of ethyl 4-bromobenzoate, where four hydrogen atoms are replaced by deuterium, serving as a stable, non-radioactive isotopic label. This compound is of significant value for research and development, particularly in analytical chemistry and pharmaceutical studies, where it is used as an internal standard for mass spectrometry to ensure accurate quantification. It is primarily needed by scientists and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for applications in drug metabolism and pharmacokinetics (DMPK) research, method development, and quality control.

Application

• Internal Standard for LC-MS/MS: Used as a high-purity, stable isotopic internal standard for the precise quantification of ethyl 4-bromobenzoate and related compounds in bioanalytical methods.
• Pharmaceutical Research: Critical in Drug Metabolism and Pharmacokinetics (DMPK) studies to track and analyze the fate of drug molecules and their metabolites.
• Metabolite Identification: Aids in the identification and structural elucidation of metabolites in complex biological matrices.
• Method Development and Validation: Employed in the development and validation of robust analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Chemical Synthesis Intermediate: Serves as a labeled building block in the synthesis of more complex deuterated molecules for research purposes.
• Quality Control & Assurance: Used in analytical laboratories to ensure the accuracy and reliability of testing procedures for related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ethyl 4-Bromobenzoate D4
CAS No.	787624-25-3
Molecular Formula	C9H5D4BrO2
Molecular Weight	229.09 g/mol
Synonyms	Ethyl 4-Bromobenzoate-d4; Ethyl p-Bromobenzoate-d4; Benzoic acid, 4-bromo-, ethyl ester-d4; 4-Bromobenzoic acid ethyl ester-d4; Ethyl 4-bromobenzoate (phenyl-d4); p-Bromobenzoic acid ethyl ester-d4; Deuterated Ethyl 4-Bromobenzoate; [2H4]-Ethyl 4-bromobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Bromobenzoate D4 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity, chemical purity, and identity. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Purity (Deuterium Content)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.